ریه، ویرایش دوم: توسعه، پیری و محیط زیست

The second edition of **The Lung: Development, Aging and the Environment** provides an understanding of the multi-faceted nature of lung development, aging, and how the environment influences these processes. As an essential resource to respiratory, pulmonary, and thoracic scientists and physicians it provides an interface between the “normal” and “disease” cluster of chapters, allowing for a natural complement to each other. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the “normal” pediatric lung. New research, including cell-based strategies for infant lung function, epigenetics, and prenatal alcohol exposure on lung development and function are some of the important additions to this edition of this reference work.* Describes the normal processes of lung development, growth and aging * Considers the effects of the environmental contaminants in the air, water, soil, and diet on lung development, growth and health * Describes genetic factors involved in susceptibility to lung disease * Covers respiratory health risk in children Content: Front Matter, Page iii Copyright, Page iv Contributors, Pages xi-xiii, Steven H. Abman, Kurt H. Albertine, Diane E. Capen, Wellington V. Cardoso, Jocelyn Claude, Candace M. Crowley, Ernest Cutz, Christopher B. Daniels, Reuben B. Dodson, Nicolle J. Domnik, Michelle Fanucchi, Michelle V. Fanucchi, John T. Fisher, Csaba Galambos, Laurel J. Gershwin, Rakesh Ghosh, Francis H.Y. Green, Richard Harding, Matt J. Herring, Irva Hertz-Picciotto, Stuart B. Hooper, et al. Introduction, Page xv, Richard Harding, Kent E. Pinkerton Chapter 1 - Lung Progenitor Cell Specification and Morphogenesis, Pages 3-9, Munemasa Mori, Wellington V. Cardoso Chapter 2 - Development of Airway Epithelium, Pages 11-32, Charles Plopper, Michelle Fanucchi Chapter 3 - Development of the Innervation of the Lower Airways: Structure and Function, Pages 33-64, Nicolle J. Domnik, Ernest Cutz, John T. Fisher Chapter 4 - The Formation of Pulmonary Alveoli, Pages 65-84, Stephen E. McGowan Chapter 5 - Pulmonary Vascular Development, Pages 85-119, Rosemary Jones, Diane E. Capen, Lynne Reid Chapter 6 - Developmental Physiology of the Pulmonary Circulation, Pages 121-136, Reuben B. Dodson, Csaba Galambos, Steven H. Abman Chapter 7 - Development of Salt and Water Transport across Airway and Alveolar Epithelia, Pages 137-155, Jonathan H. Widdicombe Chapter 8 - Physical, Endocrine, and Growth Factors in Lung Development, Pages 157-181, Megan J. Wallace, Stuart B. Hooper, Annie R.A. McDougall Chapter 9 - The Development of the Pulmonary Surfactant System, Pages 183-209, Sandra Orgeig, Janna L. Morrison, Lucy C. Sullivan, Christopher B. Daniels Chapter 10 - Ontogeny of the Pulmonary Immune System, Pages 211-222, Candace M. Crowley, Lisa A. Miller Chapter 11 - Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems, Pages 223-231, Michelle V. Fanucchi Chapter 12 - Stretch and Grow: Mechanical Forces in Compensatory Lung Growth, Pages 233-250, Connie C.W. Hsia, Cuneyt Yilmaz, Ewald R. Weibel Chapter 13 - Pulmonary Transition at Birth, Pages 251-264, Melissa L. Siew, Marcus J. Kitchen, Arjan B. te Pas, Richard Harding, Stuart B. Hooper Chapter 14 - Normal Aging of the Lung, Pages 265-285, Kent E. Pinkerton, Matt J. Herring, Dallas M. Hyde, Francis H.Y. Green Chapter 15 - Cell-Based Strategies for the Treatment of Injury to the Developing Lung, Pages 287-297, Megan O’Reilly, Bernard Thébaud Chapter 16 - Epigenetics and the Developmental Origins of Lung Disease, Pages 299-308, Lisa A. Joss-Moore, Robert H. Lane, Kurt H. Albertine Chapter 17 - Pulmonary Consequences of Preterm Birth, Pages 311-327, Kurt H. Albertine, Bradley A. Yoder Chapter 18 - The Effects of Neonatal Hyperoxia on Lung Development, Pages 329-347, Foula Sozo, Megan O’Reilly Chapter 19 - The Influence of Nutrition on Lung Development before and after Birth, Pages 349-368, Richard Harding, Robert De Matteo Chapter 20 - Genetic Factors Involved in Susceptibility to Lung Disease, Pages 369-384, Kirsten C. Verhein, Jennifer L. Nichols, Zachary McCaw, Steven R. Kleeberger Chapter 21 - Effects of Environmental Tobacco Smoke during Early Life Stages, Pages 385-397, Jingyi Xu, Suzette Smiley-Jewell, Jocelyn Claude, Kent E. Pinkerton Chapter 22 - Nicotine Exposure during Early Development: Effects on the Lung, Pages 399-411, Gert S. Maritz Chapter 23 - Exposure to Allergens during Development, Pages 413-422, Laurel J. Gershwin Chapter 24 - The Epidemiology of Air Pollution and Childhood Lung Diseases, Pages 423-437, Rakesh Ghosh, Irva Hertz-Picciotto Chapter 25 - Environmental Toxicants and Lung Development in Experimental Models, Pages 439-446, Michelle V. Fanucchi Chapter 26 - Effect of Environment and Aging on the Pulmonary Surfactant System, Pages 447-469, Sandra Orgeig, Janna L. Morrison, Christopher B. Daniels Chapter 27 - Environmental Determinants of Lung Aging, Pages 471-491, Francis H.Y. Green, Kent E. Pinkerton Index, Pages 493-499 Color Plates, Pages 1-15 The second edition of The Lung: Development, Aging and the Environment provides an understanding of the multi-faceted nature of lung development, aging, and how the environment influences these processes. As an essential resource to respiratory, pulmonary, and thoracic scientists and physicians it provides an interface between the “normal” and “disease” cluster of chapters, allowing for a natural complement to each other. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the “normal” pediatric lung. New research, including cell-based strategies for infant lung function, epigenetics, and prenatal alcohol exposure on lung development and function are some of the important additions to this edition of this reference work.

• Describes the normal processes of lung development, growth and aging
• Considers the effects of the environmental contaminants in the air, water, soil, and diet on lung development, growth and health
• Describes genetic factors involved in susceptibility to lung disease
• Covers respiratory health risk in children