Epilepsy (What Do I Do Now?)

Patients with epilpesy pose many clinical challenges. Even experienced clinicians occasionally arrive at the point where diagnostic, work-up, treatment, or prognostic thinking becomes blocked. Epilepsy is the fifth volume in the "What Do I Do Now?" series and provides the clinician with the necessary tools to evaluate and treat an epilepsy patient. Applying a case-based approach of curbside consultation, the authors present 31 actual cases, providing key points to remember and recommendations for further reading at the end of each case and including EEGs and imaging where applicable. Concise and readable, Epilepsy is the perfect quick-reference guide for anyone working with epilepsy patients. Contents 10 SECTION I: DIAGNOSTIC QUESTIONS 16 1 Febrile Seizures and Other Seizures in Infants 18 2 Benign/Idiopathic Partial Epilepsies (IPE) of Childhood 23 3 Nonconvulsive Seizures in Acutely Ill Patients 31 4 Psychogenic Nonepileptic Seizures 40 5 Frontal Lobe Seizures 47 6 Seizure Versus Parasomnias 52 7 Seizure Versus Syncope 61 SECTION II: TREATMENT CONSIDERATIONS: AEDS 66 8 First Unprovoked Seizure 68 9 Initial Treatment of Idiopathic Generalized Epilepsy 72 10 Initial Treatment of Localization-Related Epilepsy 81 11 Status Epilepticus 86 12 Adverse Effects of AEDs–Rash 92 13 Adverse Effects of AEDs–Idiosyncratic Reactions 97 14 Generic AED Substitutions 103 15 Withdrawal of AEDs 107 16 AED Failures 112 17 Drug–Drug Interactions: AEDs 117 18 Drug–Drug Interactions: Other Medications 123 19 AEDs in Pregnancy and Lactation 127 20 Treatment of Epilepsy in the Elderly 133 SECTION III: REFRACTORY EPILEPSY: DIAGNOSIS & MANAGEMENT ISSUES, INCLUDING SURGERY AND ALTERNATIVE THERAPIES 140 21 Refractory Epilepsy: General Approach 142 22 Refractory Idiopathic Generalized Epilepsy 150 23 Refractory Localization-Related Epilepsy: Extratemporal Epilepsy and Intracranial EEG Recording 154 24 Complementary and Alternative Therapies 161 SECTION IV: PROGNOSTIC, SOCIAL, AND BEHAVIORAL ISSUES 166 25 Depression in Epilepsy 168 26 Psychosis and Seizures 174 27 Cognitive and Behavioral Issues 179 28 Sleep Disturbances in Epilepsy 185 29 Bone Health 191 30 Sudden Unexpected Death in Epilepsy (SUDEP) 194 31 Work, Driving, and Epilepsy 198 Appendices 204 Index 216 A 216 B 217 C 217 D 217 E 217 F 218 G 218 H 219 I 219 J 219 K 219 L 219 M 219 N 220 O 220 P 220 R 221 S 222 T 222 V 223 W 223 Y 223 Z 223 9780199743506 Oxford University Press